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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XDH All Species: 35.45
Human Site: T1033 Identified Species: 78
UniProt: P47989 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47989 NP_000370.2 1333 146424 T1033 T D G S V L L T H G G T E M G
Chimpanzee Pan troglodytes XP_525729 1333 146376 T1033 T D G S V L L T H G G T E M G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540143 1333 147201 T1034 T D G S V L L T H G G T E M G
Cat Felis silvestris
Mouse Mus musculus Q00519 1335 146500 T1035 T D G S V L L T H G G T E M G
Rat Rattus norvegicus P22985 1331 146224 T1032 T D G S V L L T H G G T E M G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509432 1297 142673 K997 F N R E V F W K K G G L A I I
Chicken Gallus gallus P47990 1358 149595 T1061 T D G S V L L T H G G T E M G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688983 1351 148155 T1054 S D G S V L L T H G G T E M G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10351 1335 146909 S1037 G D G S V L L S H G G V E I G
Honey Bee Apis mellifera XP_001119950 1356 152206 S1061 T D G S V L I S H G G V E M G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7G192 1321 144562 V1020 L S D G T I V V E I G G I E L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 90.4 N.A. 89.1 90.3 N.A. 70.4 72.3 N.A. 67.8 N.A. 52.6 52.4 N.A. N.A.
Protein Similarity: 100 99.6 N.A. 95.4 N.A. 95.1 95.8 N.A. 82.3 84 N.A. 81.4 N.A. 69.5 70.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 20 100 N.A. 93.3 N.A. 73.3 80 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 33.3 100 N.A. 100 N.A. 86.6 93.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 52.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 82 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 10 0 0 0 82 10 0 % E
% Phe: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 82 10 0 0 0 0 0 91 100 10 0 0 82 % G
% His: 0 0 0 0 0 0 0 0 82 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 10 0 0 10 0 0 10 19 10 % I
% Lys: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 82 73 0 0 0 0 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 73 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 0 82 0 0 0 19 0 0 0 0 0 0 0 % S
% Thr: 64 0 0 0 10 0 0 64 0 0 0 64 0 0 0 % T
% Val: 0 0 0 0 91 0 10 10 0 0 0 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _